Nik Vucevic added 22 points in the Magic’s third straight win.
Rose started and played for the first time in more than a month since undergoing surgery on his right knee. The point guard was 3 of 9 from the field and finished with nine points in 19 minutes.
The Bulls had a final chance with 1.5 seconds remaining, but an inbounds pass by Mike Dunleavy to Pau Gasol at the rim sailed out of bounds.
Jimmy Butler had 19 points for Chicago. Gasol, Taj Gibson and Nikola Mirotic each added 15.