Looking like the MVP he was before being slowed by knee injuries, Rose helped the Bulls swipe home-court advantage from the Cavs, who were missing starters Kevin Love and J.R. Smith.
Jimmy Butler added 20 points and banked in a contested jumper with 30 seconds left as the Bulls closed it out.
Kyrie Irving scored 30 points and LeBron James added 19 and 15 rebounds for Cleveland, playing its first game since Love, one of the Cavs’ Big 3, was lost for the remainder of the postseason with a shoulder injury.
Game 2 is Wednesday night.
The Cavs only trailed by four points in the final minutes, but they forced several 3-point attempts and James missed a tough layup with 51 seconds left.