Wada opened the season on the disabled list with a left groin strain and made six rehab starts. He struck out seven of the first nine Padres batters.
His only mistake was allowing a two-run homer to Justin Upton to straightaway center field to give the Padres a 2-1 lead with two outs in the fourth. It was his team-leading 11th, and Derek Norris was aboard on a one-out single.
The Cubs retook the lead in the fifth against Tyson Ross (2-4). Wada drew a leadoff walk and scored on Dexter Fowler’s triple to right, just beating the relay throw by Jedd Gyorko. Fowler came in on Bryant’s sac fly to left.